DRUG METABOLISM AND DRUG INTERACTIONS
VOLUME 17, NO. 1-4, 2000
CONTENTS
Preface ..........1
Chemoprotection by
Organosulfur Inducers of Phase 2 Enzymes: Dithiolethiones and Dithiins
T.W. Kensler, T.J. Curphey,
Y. Maxiutenko and B.D. Roebuck, USA ...........3
T.J. Smith and C.S. Yang,
USA ..............23
Organosulfur Compounds from
Allium and the Chemoprevention of Cancer
A.-M. Le Bon and M.-H.
Siess, France ..............51
Allyl Sulfides Modify Cell
Growth
L.M. Knowles and J.A.
Milner,
USA ..................81
The Role of Cyclooxygenase
and Lipoxygenase in Cancer Chemoprevention
M. Cuendet and J.M. Pezzuto,
USA .............109
The Micronutrient
Indole-3-Carbinol: Implications for Disease and Chemoprevention
H.G. Shertzer and A.P.
Senft, USA ...............159
Carotenoids and Chronic
Diseases
S. Agarwal and A.V. Rao,
Canada ................189
The Bioactivity of
Saponins: Triterpenoid and Steroidal Glycosides
A.V. Rao and D.M.
Gurfinkel, Canada
...............211
Molecular Aspects of
Procyanidin Biological Activity: Disease Preventative and Therapeutic
Potentials
H. Moini, G. Rimbach, and
L. Packer, USA ..............237
Promotion of Health by Soy
Isoflavones: Efficacy, Benefit and Safety Concerns
S. Goldwyn, A. Lazinsky and
H. Wei, USA ...........261
Bioavailability of Flavonoids
and Potential Bioactive Forms in Vivo
C. Rice-Evans, J.P.E.
Spencer, H. Schroeter and A.R. Rechner, UK ............291
Cancer Chemoprevention and
Apoptosis Mechanisms Induced by Dietary Polyphenolics
G. Galati, S. Teng, M.Y.
Moridani, T.S. Chan and P.J. O達rien, Canada ............311
Effect of the Grapefruit
Flavonoid Naringin on Pharmacokinetics of Quinine in Rats
H. Zhang, C.W. Wong, P.F.
Coville and S. Wanwimolruk, New Zealand .............351
Index ............365