DRUG METABOLISM
AND
DRUG INTERACTIONS
VOLUME 18, NO. 2, 2001
CONTENTS
A Review of Xenobiotic Metabolism Enzymes in Parkinson痴 Disease and
Motor Neuron Disease
G.B.
Steventon, S. Sturman, R.H. Waring and A.C. Williams, UK ......79
Effect of Ubidecarenone on Warfarin Anticoagulation
and Pharmacokinetics of Warfarin Enantiomers in Rats
Stephanie
Zhou and Eli Chan, Singapore ...........99
Time-Dependent Pharmacokinetic Interaction Between
Zidovudine and Rifampicin Following Oral Administration of the Combination at 1000
and 2200 Hours
R. Karwa,
A. Shashank, D. Rambhau, D. Gopinath and D. Ravi, India .............123
Interspecies Scaling: Is a priori Knowledge of
Cytochrome P450 Isozymes Involved in Drug Metabolism Helpful in Prediction of
Clearance in Humans from Animal Data?
I.
Mahmood, USA .........135
17b-Estradiol Stimulates Mineralized Bone Nodule
Formation when Added Intermittently to SaOS-2 Cells
L.G. Rao,
L.J.-F. Liu, T.M. Murray and E. McDermott, Canada ........149
ｩ Freund
Publishing House Ltd. 2001