DRUG METABOLISM
AND
DRUG INTERACTIONS
VOLUME 19, NO. 2, 2002
CONTENTS
Effects of Amifostine on Liver Oxidative Stress Caused by Cyclophosphamide Administration to Rats
A. Stankiewicz, E. Skrzydlewska and M. Makieła, Poland .........67
Effects
of Food on Ethanol Metabolism
D. Whitmire,
L. Cornelius and P. Whitmire, USA ...........83
Molecular
Modelling of the Mouse Cytochrome P450 CYP2F2 Based on the CYP102 Crystal
Structure Template and Selective CYP2F2 Substrate Interactions
D.F.V. Lewis, P.T. Bailey and L.K. Low, UK and USA ...........97
Molecular
Modelling of CYP2B6 Based on Homology with the CYP2C5 Crystal Structure:
Analysis of Enzyme-Substrate Interactions
D.F.V. Lewis, B.G. Lake, M. Dickins and P.S.
Goldfarb, UK ........115
Influence
of Multiple Dose Activated Charcoal on the Disposition Kinetics of Irinotecan
in Rats
C. Balram, Q.-Y. Zhou, Y.B. Cheung and E.J.D. Lee, Singapore .......137
Book Review .........149
ｩ Freund
Publishing House Ltd. 2002