DRUG METABOLISM AND
DRUG INTERACTIONS

VOLUME 19, NO. 4, 2003

CONTENTS

An Investigation into the Inter-Relationships of Sulphur Xeno-Biotransformation Pathways in Parkinson’s and Motor Neurone Diseases

G.B. Steventon, R.H. Waring and A.C. Williams, UK .........223

Degradation to Sulphate of S-Methyl-L-Cysteine Sulphoxide and S-Carboxymethyl-L-Cysteine Sulphoxide in Man

R.H. Waring, R.M. Harris, G.B. Steventon and S.C. Mitchell, UK .......241

Investigation of Enzyme Selectivity in the Human CYP2C Subfamily: Homology Modelling of CYP2C8, CYP2C9 and CYP2C19 from the CYP2C5 Crystallographic Template

D.F.V. Lewis, M. Dickins, B.G. Lake and P.S. Goldfarb, UK ..........257

Influence of Rifampicin Pretreatment on the Pharmacokinetics of Celecoxib in Healthy Male Volunteers

G. Jayasagar, M. Krishna Kumar, K. Chandrasekhar and Y. Madhusudan Rao, India ..........287

Index ............297