JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM

VOLUME 11, SUPPLEMENT 3, DECEMBER, 1998

CONTENTS

Introduction

R. Stanhope, UK ...... 771

 

Multicentre Study on Prevalence of Fractures in Transfusion-Dependent Thalassaemic Patients

L. Ruggiero and V. de Sanctis, Italy ........... 773

 

Bone Pain In Thalassaemia: Assessment of DEXA and MRI Findings

M. Angastiniotis, N. Pavlides, K. Aristidou, A. Kanakas, M. Yerakaris, E. Eracleous and Th. Posporis, Cyprus ........... 779

 

Bone Density and Metabolism in Thalassaemia

R. Lala, P. Chiabotto, M. Di Stefano, G. C. Isaia, F. Garofalo and A. Piga, Italy ............. 785

 

pQCT (Quantitative Peripheral Tomography) and Data Evaluation of Phosphocalcic Metabolism in Thalassaemic Patients

B. Bagni, G. Palazzi, I. Bagni, C. Caporali, W. Froehlich, A. Casolo, C. Caputo, S. Rossi, E. Garetti, F. Pansini, T. Corazzari, V. De Sanctis and F. Massolo, Italy ................ 791

 

Genetic and Acquired Predisposing Factors and Treatment of Osteoporosis in Thalassaemia Major

B. Wonke, C. Jensen, J.J. Hanslip, E. Prescott, M. Lalloz, M. Layton, S. Erten, S. Tuck, J.E. Agnew, K. Raja, K. Davies and A.V. Hoffbrand, UK ............ 795

 

The Diagnosis of Childhood Growth Hormone Insufficiency and Growth Hormone Resistance

S.A. McGrath and P.M.G. Bouloux, UK ............ 803

 

Short Stature and Body Proportion in Thalassaemia

M. Caruso-Nicoletti, V. De Sanctis, M. Capra, G. Cardinale, L.Cuccia, F. Di Gregorio, A. Filosa, M.C. Galati, A. Lauriola, R. Malizia, A. Mangiagli, F. Massolo, C. Mastrangelo, A. Meo, M.F. Messina1, G. Ponzi, G. Raiola, L. Ruggiero, G. Tamborino and A. Saviano, Italy ......... 811

 

Long Term Follow-up of Skeletal Dysplasia in Thalassaemia Major

A. Naselli, M. Vignolo, E. Di Battista, P. Garzia, G.L. Forni, T. Traverso and G. Aicardi, Italy ............. 817

 

Growth Hormone Secretion and Bone Histomorphometric Study in Thalassaemic Patients with Acquired Skeletal Dysplasia Secondary to Desferrioxamine

V. De Sanctis, S. Stea, L. Savarino, V. Scialpi, G.C. Traina, G.M. Chiarelli, M. Sprocati, R. Govoni, D. Pezzoli, R. Gamberini and F. Rigolin, Italy ............ 827

 

Growth and Management of Short Stature in Thalassaemia Major

C. Theodoridis, V. Ladis, A. Papatheodorou, H. Berdousi, F. Palamidou, C. Evagelopoulou, K. Athanassaki, O. Konstantoura and C. Kattamis, Greece ............ 835

 

Short-Term Therapy with Recombinant Growth Hormone in Polytransfused Thalassaemia Major Patients with Growth Deficiency

L. Cavallo, R. Gurrado, C. Zecchino, F. Manolo, V. De Sanctis, M. Cisternino, M. Caruso Nicoletti and M. Galati, Italy ......... 845

 

Acute Metabolic Effects of Human Growth Hormone on 15N-Nitrogen Balance in Patients with Thalassaemia as Compared to
Patients with Other Types of Short Stature

Milo Zachmann, Bianca Kempken and Vincenzo De Sanctis, Switzerland and Italy ............. 851

 

New GH Secretagogues and Potential Usefulness in Thalassemia

I. Karydis, A. Tolis and G. Tolis, Greece and Canada ........... 857

 

Glucose Tolerance, Insulin Secretion and Peripheral Sensitivity in Thalassaemia Major

T. Arrigo, G. Crisafulli, A. Meo, M. Sturiale, F. Lombardo, M. Miceli, D. Cucinotta and F. De Luca, Italy ........... 863

 

Epidemiology and Chelation Therapy Effects on Glucose Homeostasis in Thalassaemic Patients

M.R. Gamberini, M. Fortini, G. Gilli, M.R. Testa and V. De Sanctis, Italy ........... 867

 

Glucose Disturbances and Regulation with Glibenclamide in Thalassemia

V. Ladis, C. Theodorides, F. Palamidou, S. Frissiras, H. Berdousi and C. Kattamis, Greece .......... 871

 

Prevalence of Retinopathy in Diabetic Thalassaemic Patients

C. Incorvaia, F. Parmeggiani, G. Mingrone, A. Sebastiani and V. De Sanctis, Italy ............. 879

 

Hormonal Replacement Therapy with HCG and HU-FSH in Thalassaemic Patients Affected by Hypogonadotropic Hypogonadism

M. Cisternino, S. Magni Manzoni, E. Coslovich and M. Autelli, Italy ............. 885

 

Clinical Experience Using the Androderm® Testosterone Transdermal System in Hypogonadal Adolescents and Young Men with b-Thalassemia Major

V. De Sanctis, C. Vullo, L. Urso, F. Rigolin, A. Cavallini, K. Caramelli, C. Daugherty and N. Mazer, Italy and USA ............ 891

 

Transfusional Transmitted Viruses in Pregnancy

A. Eleftheriou, G. Kalakoutis and N. Pavlides, Cyprus ............ 901

 

Thrombotic Risk In Thalassemic Patients

S. Moratelli, V. De Sanctis, D. Gemmati, M.L. Serino, R. Mari, M.R. Gamberini and G.L. Scapoli, Italy ............ 915

 

Pregnancy Management and Outcomes in Women with Thalassaemia Major

S.M. Tuck, C.E. Jensen, B. Wonke and A. Yardumian, UK ............... 923

 

Preliminary Observations about Assisted Reproduction in Thalassaemia

P. Negri, V. De Sanctis, E. Grechi, M.R. Gamberini and L. Urso, Italy ............... 929

 

Fertility in Female Patients with Thalassemia

N. Skordis, S. Christou, M. Koliou, N. Pavlides and M. Angastiniotis, Cyprus ................... 935

 

Fertility in Thalassemia: The Greek Experience

M. Karagiorga-Lagana, Greece ............. 945

 

POSTERS

 

Glucose Intolerance in Patients with Thalassemia Major: Insulin Resistance and Hyperproinsulinemia

H. Cario, R.W. Holl and E. Kohne, Germany ........... 953

 

Growth Failure and Bone Lesions due to Desferrioxamine in Thalassaemic Patients

M. Caruso-Nicoletti, D. Di Bella, G. Pizzarelli, C. Leonardi, C. Sciuto, M. Coco and F. Di Gregorio, Italy .............. 957

 

Evaluation of Spine and Hip Bone Density by DXA and QCT in Thalassemic Patients

L. Danesi, R. Cherubini, L. Ciceri, G. Graziadei, M.D. Cappellini, F. Cavagnini and S. Ortolani, Italy ............. 961

 

Bone Density Study of Thalassemic Patients from Reggio Calabria Province

D.G. D’Ascola, M. Caminiti, G. Pagano Mariano, C. Giuffrè, S. Parlongo, P. Meduri and M. Brugiatelli, Italy ............... 963

 

Final Height and Endocrine Function in Thalassaemia Intermedia

V. De Sanctis, A. Tangerini, M.R. Testa, A.L. Lauriola, M.R. Gamberini, A.R. Cavallini and F. Rigolin, Italy ............. 965

 

b-Cell Secretion in Thalassemia Major Patients

E. Ferrari, A. Bergomi, G. Palazzi, S. Rossi, S. Forese and F. Massolo, Italy ................973

 

High Incidence of Osteoporosis in Thalassaemia Major

C.E. Jensen, S.M. Tuck, J.E. Agnew, S. Koneru, R.W. Morris, A. Yardumian, E. Prescott, A.V. Hoffbrand and B. Wonke, UK ........... 975

 

Rachitic Rosary in a Well Chelated Thalassaemic Patient with Primary Amenorrhea (Patient Report)

A.L. Lauriola, A. Tangerini, A. Lodi, M.R. Gamberini, M.R. Testa, C. Orzincolo, V. De Sanctis and C. Vullo, Italy .............. 979

 

Zinc Deficiency and Cell-Mediated and Humoral Autoimmunity of Insulin-Dependent Diabetes in Thalassemic Subjects

R. Malizia, A. Scorsone, P. D’Angelo, C. Lo Pinto, L. Pitrolo and C. Giordano, Italy .............. 981

 

Glucose Tolerance and b-Cell Secretion in Patients with Thalassaemia Major

A. Mangiagli, S. Italia and S. Campisi, Italy ............. 985

 

Induction of Ovulation in Thalassemic Patients

C. Pafumi, L. Ciotta, G. Pernicone, M.A. Palumbo, F. Di Gregorio, M. Caruso-Nicoletti, M. Conversano, A. Cianci and G. Palumbo, Italy ..........987

 

Osteopenia in Female b-Thalassemic Patients

C. Pafumi, L. Roccasalva, G. Pernicone, G. Spanò, M.A. Palumbo, F. Di Gregorio, M. Caruso-Nicoletti, M. Conversano, A. Cianci and G. Palumbo, Italy ........... 989

 

Screening for Beta-Thalassemia Heterozygotes in Pregnant Women

C. Pafumi, A. Moschetto, G. Pernicone, M.A. Palumbo, L. Chinnici, A. Cianci and G. Palumbo, Italy ........... 993

 

Human Chorionic Gonadotrophin Therapy in Hypogonadal Thalassaemic Patients with Osteopenia: Increase in Bone Mineral Density

R. Perniola, C. De Rinaldis and M. Muratore, Italy ............ 995

 

Pituitary Deficiency and Lack of Gonads in an XY Pseudohermaphrodite with b39/Lepore Haemoglobinopathy

A. Saviano, A. Filosa, D. Pasquali, M. Lamba, M.C. Siciliani, M.M. Rinaldi, A. Bellastella, and A.A. Sinisi, Italy .............. 997

 

An Endocrinologist’s Commentary

R. Stanhope, UK ............ 1001

 

Indexes.............. 1003

©Freund Publishing House Ltd. 1998

 

ISSN 0334-018X/11-S3

232 pages

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