JOURNAL OF

PEDIATRIC ENDOCRINOLOGY & METABOLISM

VOLUME 12, NUMBER 4, JULY-AUGUST 1999

TABLE OF CONTENTS

REVIEWS

Targeted Gene Mutations Define the Roles of Insulin and IGF-I Receptors in Mouse Embryonic Development

D. Accili, J. Nakae, J.J. Kim, B.-C. Park and K.I. Rother, Bethesda, MD, USA ......... 475

Maturity-Onset Diabetes of the Young (MODY): A New Challenge for Pediatric Diabetologists

L. Guazzarotti, E. Bartolotta and F. Chiarelli, Recanati and Chieti, Italy .......... 487

ORIGINAL CONTRIBUTIONS

Insulin-like Growth Factor-I Treatment in Two Children with Growth Hormone Gene Deletions

I.J.P. Arnhold, S.B. Oliveira, M.G.F. Osorio and B.B. Mendonca, São Paulo, Brazil ........... 499

Body Mass Index is Different in Normal Chinese and Caucasian Infants

S.Y.M. Tam, J.P.E. Karlberg, E.Y.W. Kwan, A.M.C. Tsang, H.P. Sheng, Q. He and L.C.K. Low, Hong Kong, PR China ......... 507

Bone Mineral Density and Metabolism in Children Treated with L-Thyroxine

L. Tümer, A. Hasanoğlu, P. Cinaz and A. Bideci, Ankara, Turkey ......... 519

Bone Age Progression During Five Years of Substitutive Therapy for the Induction of Puberty in Thalassemic Girls - Effects on Height and Sitting Height

A. Filosa, S. Di Maio, M. Lamba, I. Baron, A. Saviano and G. Esposito, Naples, Italy ........... 525

Long-Term Treatment with GHRH [1-44] Amide in Prepubertal Children with Classical Growth Hormone Deficiency

S.C. Duck and R. Rapaport, Evanston, IL and Newark, NJ, USA .......... 531

Factors at Onset Predictive of Lasting Remission in Paediatric Patients with Graves’ Disease Followed for at Least Three Years

G.C. Mussa, A. Corrias, L. Silvestro, E. Battan, M. Mostert, F. Mussa and D. Pellegrino, Turin, Italy ........... 537

Urinary Free Cortisol (UFC) Values in Newborns Under Stress

Z. Zadik, R. Amer, Z. Dolfin, S. Arnon, D. Cohen, B. Mogilner and R. Reifen, Rehovot, Kfar Saba and Jerusalem, Israel ........ 543

Parenteral Nutrition-Associated Cholestasis in Preterm Neonates: Evaluation of Ursodeoxycholic Acid Treatment

A. Levine, A. Maayan, R. Shamir, G. Dinari, J. Sulkes and L. Sirotta, Petah Tikva and Tel Aviv, Israel ......... 549

SHORT COMMUNICATION

Bisphosphonates in Children with Osteogenesis Imperfecta may Improve Bone Mineralization but not Bone Strength. Report of Two Patients

E.J.A. Roldán, T. Pasqualini and L. Plantalech, Buenos Aires, Argentina ............ 555

PATIENT REPORTS

Precocious Puberty in a Patient with Indicanuria

B. Büyükgebiz, A. Uğuz, E. Böber and A. Büyükgebiz, Izmir, Turkey ......... 561

Robinow Syndrome with Growth Hormone Deficiency: Treatment with Growth Hormone

S. Castells, A. Chakurkar, Q. Qazi and W. Bastian, Brooklyn, NY, USA ......... 565

Ectopic ACTH Syndrome due to Thymic Carcinoid Tumor in a Girl

K.-L. Lin, C.-Y. Chen, H.-H. Hsu, P.-F. Kao, M.-J. Huang and H.-S. Wang, Taiwan ......... 573

Pheochromocytoma and Clear-Cell Renal Carcinoma in a Child with von Hippel-Lindau Disease: A Patient Report

J. Ferragut, M. Caimari, B. Rituerto, B. Gómez-Rivas, M. Herrera and F. Alonso, Palma de Mallorca, Spain ........... 579

FORUM AND CORRESPONDENCE .......... 583

BOOK REVIEWS ........... 585

MEETINGS CALENDAR ............. 587