JOURNAL OF

PEDIATRIC ENDOCRINOLOGY & METABOLISM

VOLUME 12, SUPPLEMENT 3, NOVEMBER 1999

Future Perspectives in Childhood Diabetes

Selected Papers from the ISPAD Postgraduate Course held in Garda, Italy, April 1999

Guest Editors: Leonardo Pinelli (Italy) and Zvi Laron (Israel)

TABLE OF CONTENTS

Foreword ........ 719

The Mechanism of Insulin Action

J. Nakae and D. Accili, USA .......... 721

Lessons From Recent Epidemiological Studies in Type 1 Childhood Diabetes

Z. Laron, Israel ........... 733

Rationale for Using Combinations of Short-Acting Insulin Analogue and NPH Insulin at Mealtime in the Treatment of Type 1 Diabetes Mellitus

G.B. Bolli, Italy ........... 737

Long Acting Insulin Analogues: Can they Provide a Basal Insulin Level?

T.R. Pieber, Austria ........... 745

The MiniMed Continuous Glucose Monitoring System (CGMS)

J. Mastrototaro, USA ........... 751

Insulin Pump Therapy in Type 1 Pediatric Patients

F.R. Kaufman, M. Halvorson, L. Fisher and P. Pitukcheewanont, USA ............. 759

Advances in Pancreas Transplantation 1999. Indications and Contraindications

J.M. Dubernard, C. Martin, N. Lefrancois, C.H. Thivolet, M. Dawahra, P. Petruzzo and X. Martin, France .............. 765

Islet Transplantation in Diabetic Patients

F. Bertuzzi, A. Secchi, L. Aldrighetti, R. Nano, G. Pozza and V. Di Carlo, Italy ........... 771

Effects of Pancreas Transplantation on Late Complications of Diabetes and Metabolic Effects of Pancreas and Islet Transplantation

R. Caldara, E. La Rocca, P. Maffi and A. Secchi, Italy ......... 777

Gene Therapy for Beta-Cell Functional Replacement in IDDM

L. Falqui, Italy ............ 789

Childhood Obesity: Results of a Multicenter Study of Obesity Treatment in Italy

L. Pinelli, N. Elerdini, M.S. Faith, D. Agnello, A. Ambruzzi, M. De Simone, G. Leggeri, C. Livieri, N. Monetti, P. Peverelli, A. Salvatoni, S. Seminara, R. Uasone and A. Pietrobelli, Italy and USA ........ 795

ISSN 0334-018X/12-S3

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