JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM

VOLUME 13,  SUPPLEMENT 5  (2002)

Developmental Aspects of Androgen Excess Disorders: 2nd International Symposium, Canada, June 200

Guest Editors: R. Azziz and P. Saenger

 

Preface ........  1245

 

Section I: Premature Adrenarche and the Polycystic Ovary Syndrome

The Natural History of Premature Adrenarche

L. Ghizzoni and S. Milani, Italy ....................  1247

 

Adrenarche and Nutritional Status

T. Remer, Germany ...............  1253

 

Syndrome X: A Consequence of Intra-Uterine Malnutrition?

J. Léger, D. Jaquet, C. Lévy-Marchal and P. Czernichow, France .............  1257

 

Precocious Pubarche in Girls and the Development of Androgen Excess

L. Ibáñez, N. Potau, D. Dunger and F. de Zegher, Spain, UK and Belgium ................  1261

 

Pre- and Postpubertal Findings in Premature Adrenarche

J. DiMartino-Nardi, USA ................  1265

 

Section II: Steroidogenic/Gonadotropic Abnormalities in the Polycystic Ovary Syndrome

The Function and Roles of P450c17 in Androgen Excess States

R.J. Auchus, D.H. Geller, T.C. Lee and K.M. Worthy, USA .................  1271

 

Sex Hormone-Binding Globulin During Puberty in Normal and Hyperandrogenic Girls

M. Pugeat, P. Cousin, C. Baret, H. Lejeune and M.G. Forest, France ..................  1277

 

The Gonadotropic Axis in Hyperandrogenic Adolescents

A.E. Taylor, USA ......................  1281

 

Diagnosis of the Polycystic Ovary Syndrome in Adolescence: Comparison of Adolescent and Adult Hyperandrogenism

R.L. Rosenfield, K. Ghai, D.A. Ehrmann and R.B. Barnes, USA ..........................  1285

 

Section III: Abnormalities of Insulin Action in the Polycystic Ovary Syndrome

Molecular Defects of Insulin Action in the Polycystic Ovary Syndrome: Possible Tissue Specificity

T.P. Ciaraldi, USA ...................  1291

 

Role of Inositolphophoglycan Mediators of Insulin Action in Polycystic Ovary Syndrome

J.E. Nestler, D.J. Jakubowicz and M.J. Iuorno, USA and Venezuela ..............  1295

 

Glucose Intolerance in the Polycystic Ovary Syndrome: Role of the Pancreatic Beta-Cell

D.A. Ehrmann, USA ..................  1299

 

Section IV: Genetics of the Polycystic Ovary Syndrome

Family History as a Risk Factor for the Polycystic Ovary Syndrome

R. Azziz and M.D. Kashar-Miller, USA ...........  1303

 

Is There a Male Phenotype in Polycystic Ovary Syndrome Families?

R.S. Legro, USA ..............  1307

 

Searching for the Polycystic Ovary Syndrome Genes

M. Urbanek, R.S. Legro, D. Driscoll, J.F. Strauss, III, A. Dunaif and R.S. Spielman, USA .........  1311

 

The Role of Heterozygosity for CYP21 in the Polycystic Ovary Syndrome

S.F. Witchel and C.E. Aston, USA ...............  1315

 

   

 

ISSN 0334-018X/13-S5

76 pages

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